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View compareAlpha-Lipoic acid (ALA) R+ is the only antioxidant that is both fat- and water-soluble. This is important because alpha-lipoic acid can access all parts of living cells, giving it the ability to trap free radicals and help protect against oxidation. ALA R+ is one of the few substances that can cross the blood-brain barrier. ALA supplementation supports healthy glutathione levels, which helps the body metabolize toxins.*